Mapping vertebrate embryos

Mapping vertebrate embryos

A major challenge in embryology is to understand how cells become specialized into distinct lineages and assembled into a pattern of tissues that will make up the embryo. The discovery that patterns of gene expression are conserved among embryos of the favourite vertebrate species for laboratory study — zebrafish, frog (Xenopus), chick and mouse — has led to a surge of interest in finding out h...

The Culture of Vertebrate Embryos

THE CULTURE OF VERTEBRATE EMBRYOS. By D. A. T. New. New York and London, Academic Press, 1966. 245 pp. $14.00. The purpose of this book, as set forth in the introduction, is to describe available methods for the culture of vertebrate embryos and to note some experiments that have been performed on such embryos. It is intended to benefit both the research scientist and the biology teacher; the u...

Ectodermal patterning in vertebrate embryos.

Recent molecular insights on how the ectodermal layer is patterned in vertebrates are reviewed. Studies on the induction of the central nervous system (CNS) by Spemann's Organizer led to the isolation of noggin and chordin. These secretory proteins function by binding to, and inhibiting, ventral BMPs, in particular BMP-4. Neural induction can be considered as the dorsalization of ectoderm, in w...

Differential gene expression in vertebrate embryos.

Theinvitation to contribute to the Reflections series in the Journal of Biological Chemistry is an honor that I greatly appreciate. It is humbling to find oneself in such distinguished company and a challenge to the literary limitations reflected all too obviously in the scientific writing I usually engage in. What I would like to do is to describe my own professional path in the context of the...

PCP Signaling and Ciliogenesis in Vertebrate Embryos